e-ISSN 2320-2955, p-ISSN 2249-2569, ISBN 978-81-909047-9-7
INTERNATIONAL RESEARCH JOURNAL OF HUMANITIES,
ENGINEERING & PHARMACEUTICAL SCIENCES
(An International Registered Research Journal) - Now IJHEPS Recommended By International Committee of Medical Journal Editors, USA
- Now IJHEPS Recommended By International Committee of Medical Journal Editors, USA
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| Title | SYNTHESIS OF SOME NOVEL PIPERAZINE SALTS AND THEIR ANTIMICROBIAL PROPERTY AGAINST STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA |
| Authors | Deepa Lakhmani,Krishna Srivastava, Sunil Kumar |
| Page No | 9-12 |
| Code | Int./JUNE19/PH1806 |
| Affiliation | Shri Ramswaroop Memorial University |
| Abstract | The synthesis of 4-methyl-1H-isochrome-1-one 1(a-e) different type of coumarin derivatives have been performed from different type of phenol derivatives. The compound 1(a-e) were then converted to their respective compound 2(a-e) by react with benzoic acid to gave 4-(4-methyl-1-oxoisoquinolin-2(1H)-yl)benzoic acid. The compound 2(a-e) on heating with piperazine hydrate to gave compound 3(a-e) Piperazine1-4-bis-[-2-aryl/alkyl-4-arylidene/alkylidene-5-oxo-imidazolyl]-1-phenyl-4carboxylates.The new compounds have been screened for their antimicrobial activity. |
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