INTERNATIONAL RESEARCH JOURNAL OF HUMANITIES,
ENGINEERING & PHARMACEUTICAL SCIENCES

Dipti Mani Tripathi, Deepa Lakhmani, Raj Bahadur Singh, Krishna Srivastava, Ravi Kant

Shri Ramswaroop Memorial University, Barabanki, Uttar Pradesh, India

The present manuscript deals the design, synthesis, structural and biomedicinal characterization of some organic derivatives of bismuth which were synthesized by the method reported earlier and characterized with the help of M.P., elemental, I.R., and NMR spectral analysis along with their in-vitro antitumor activity against human breast (MCF-7) and mammary cancer (EVSA-7) cell line and found that compounds have potentiality as antitumor agents. The compounds were also tested for gastroprotective (Anti-ulcer) activity in rats using standard methods. These organobismuth compounds exhibit higher activity than the standard ranitidine when the tests were carried out with aspirin (ASP) induced and moderate activity was seen when the tests were done with ethanol (EtOH) induced.