International Journal of Humanities, Engineering and pharmaceutical science | IJHEPS | International Pharma Journal | Callofpaper IJHEPS

e-ISSN 2320-2955, p-ISSN 2249-2569, ISBN 978-81-909047-9-7

INTERNATIONAL RESEARCH JOURNAL OF HUMANITIES,
ENGINEERING & PHARMACEUTICAL SCIENCES

(An International Registered Research Journal)

IJHEPS NEW




PHARMACY
Title SYNTHESIS AND ANTIFUNGAL EVALUATION OF OXADIAZOLE DERIVATIVES
Authors Dr.Kiran Mishra
Page No 97-100
Code Int./JUNE14/PH809
Affiliation Gurukul Vidyapeeth Institute of Engineering & Technology Ramnagar, Banur, Punjab
Abstract

The objective of present research work is to synthesis of a number of 1, 3, 4-oxadiazole derivatives for antifungal activity. Some of the synthesized compounds showed significant antifungal activity. KM-8 compound exhibited potent activity (MIC=12.5 μg/ml). The synthesized derivatives were characterized by means of TLC, IR, and 1HNMR spectral analysis for their structural confirmation. The derivatives which showed better antifungal activity may serve as leads for further optimization.

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